No label defined (Q33348)

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  • Early adopters of doxycycline as post-exposure prophylaxis to prevent bacterial sexually transmitted infections in a real-world clinical setting.
Language Label Description Also known as
English
No label defined
No description defined
  • Early adopters of doxycycline as post-exposure prophylaxis to prevent bacterial sexually transmitted infections in a real-world clinical setting.

Statements

Early adopters of doxycycline as post-exposure prophylaxis to prevent bacterial sexually transmitted infections in a real-world clinical setting. (English)
1 reference
Doxycycline as post-exposure prophylaxis (DoxyPEP) is a novel prevention approach which has demonstrated efficacy in preventing bacterial sexually transmitted infections (STIs) in men who have sex with men (MSM) and transgender women (TGW) including people who are living with HIV and those on HIV pre-exposure prophylaxis (PrEP). (English)
OBJECTIVES (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
We evaluated patient knowledge and interest in DoxyPEP, as well as early adopters of its use. (English)
OBJECTIVES (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
In 2023, patients presenting for HIV and STI services at a primary care and sexual health clinic were asked about DoxyPEP knowledge, interest and use. (English)
METHODS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
Bivariate and multivariate analyses were used to evaluate demographics and behaviours associated with these outcomes. (English)
METHODS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
A total of n=421 people presented for care. (English)
RESULTS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
Of these, 314 were MSM/TGW. (English)
RESULTS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
Fifteen percent were Black/African-American, and 21% were Hispanic/Latino. (English)
RESULTS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
A total of 50% of MSM/TGW had heard of DoxyPEP, 49% were interested and 18% reported prior DoxyPEP use. (English)
RESULTS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
Having a history of STI infection ever (adjusted OR (aOR) 5.95, 95% CI 2.69 to 13.13) and in the past 12 months (aOR 2.99, 95% CI 1.56 to 5.72) were both associated with DoxyPEP use. (English)
RESULTS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
Individuals who had ever used HIV PrEP had nearly three times the odds of ever taking DoxyPEP (aOR 2.88, 95% CI 1.56 to 5.30). (English)
RESULTS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
There was no association between the use of DoxyPEP and race, ethnicity or HIV status. (English)
RESULTS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
Among MSM and TGW, there is already significant awareness, interest and use of DoxyPEP to prevent bacterial STIs. (English)
CONCLUSIONS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
1 reference
Public health efforts should focus on improving access and delivery of this STI prevention intervention to MSM and TGW. (English)
CONCLUSIONS (English)
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ. (English)
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19 August 2024
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19 August 2024
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100
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6
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339-342
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339
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342
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Competing interests: None declared. (English)
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