No label defined (Q32297)
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- Prospective longitudinal study of men who have sex with men and transgender women to determine HIV incidence in two provinces in Thailand.
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English | No label defined |
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Statements
In Thailand, HIV transmission is well characterized in large urban centers such as Bangkok and Chiang Mai but less so outside of these areas. (English)
BACKGROUND (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
The main purpose of this study was to assess HIV incidence and associated risk factors in Nakhon Ratchasima and Ratchaburi. (English)
BACKGROUND (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
Participants assigned male sex at birth were enrolled in this prospective observational cohort study between November 2017 and July 2018. (English)
METHODS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
HIV and syphilis testing and sociobehavioral questionnaires were administered over 18 months. (English)
METHODS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
HIV incidence rates and 95% confidence intervals (CIs) were estimated using a Poisson distribution. (English)
METHODS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
Cox proportional hazards models were used to estimate unadjusted and adjusted hazard ratios (aHRs) and 95% CIs for associations between potential risk factors and HIV seroconversion. (English)
METHODS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
A total of 1003 participants were enrolled. (English)
RESULTS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
Overall HIV incidence was 1.56 per 100 person-years (95% CI:1.02-2.44) and similar at both sites. (English)
RESULTS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
In the fully adjusted model, sex with a sex worker in the past six months was associated with reduced risk of seroconversion (aHR:0.10, 95% CI:0.01-0.77). (English)
RESULTS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
In the reduced adjusted model, receptive anal sex (aHR:3.40, 95% CI:1.32-8.74) and STI diagnosis in the past six months (aHR:3.58, 95% CI:1.19-10.76) were associated with seroconversion, while sex with a sex worker in the past six months was associated with reduced risk of seroconversion (aHR:0.11, 95% CI:0.02-0.67). (English)
RESULTS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
Additionally, 56% reported interest in taking PrEP and 82% reported willingness to participate in a hypothetical future vaccine trial. (English)
RESULTS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
Recent receptive anal sex practices were associated with HIV acquisition in these populations, highlighting the continued need for interventions encouraging safer anal sex practices to reduce HIV incidence. (English)
CONCLUSIONS (English)
Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. (English)
Chawetsan (English)
Namwat (English)
C
Warong (English)
Leela-Apiradee (English)
W
Thawat (English)
Tiawilai (English)
T
Tanyaporn (English)
Wansom (English)
T
Suchai (English)
Kitsiripornchai (English)
S
Nakorn (English)
Premsri (English)
N
Siriwat (English)
Akapirat (English)
S
Trevor A (English)
Crowell (English)
TA
Leilani (English)
Francisco (English)
L
Merlin L (English)
Robb (English)
ML
Kirsten S (English)
Smith (English)
KS
Elizabeth A (English)
Heger (English)
EA
Mark M (English)
Fukuda (English)
MM
Robert J (English)
O'Connell (English)
RJ
Supachai (English)
Rerks-Ngarm (English)
S
Sandhya (English)
Vasan (English)
S
14 November 2024
14 November 2024