The vaginal microbiome of transgender men receiving gender-affirming hormonal therapy in comparison to that of cisgender women (Q28918)

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  • The vaginal microbiome of transgender men receiving gender-affirming hormonal therapy in comparison to that of cisgender women.
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English
The vaginal microbiome of transgender men receiving gender-affirming hormonal therapy in comparison to that of cisgender women
No description defined
  • The vaginal microbiome of transgender men receiving gender-affirming hormonal therapy in comparison to that of cisgender women.

Statements

The vaginal microbiome of transgender men receiving gender-affirming hormonal therapy in comparison to that of cisgender women. (English)
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The vaginal microbiome of trans men and menopausal women is suspected to be similar due to a lack of estrogen leading to the absence of lactobacilli. (English)
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We performed an analysis of the vaginal microbiome of trans men (n = 25) in comparison to that of menopausal (n = 25) and premenopausal women (n = 25). (English)
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The vaginal microbiome of trans men and menopausal women showed a higher alpha diversity than that of premenopausal women. (English)
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Various beta diversity indices (e.g., Bray‒Curtis (Un-)Weigthed Unifrac), showed significant differences in community composition between trans men and premenopausal (p < 0.001) and menopausal women (p < 0.001). (English)
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The vaginal microbiome of trans men is characterized by a loss of Lactobacillus and an increase in bacteria associated with the intestinal flora (e.g., Campylobacter, Anaerococcus, Dialister, Prevotella). (English)
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The abundance of Dialister and Prevotella decreased with the length of hormonal therapy in trans men. (English)
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The Nugent score, Pap smear and HPV status did not differ between the study groups. (English)
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The vaginal microbiome of trans men differs from that of premenopausal women but shows similarities to that of menopausal women. (English)
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The duration of hormonal therapy in trans men may have important impacts on the vaginal microbiome and thus possibly on the risk for STIs. (English)
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14 September 2024
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14 September 2024
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21526
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21526
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The authors declare no competing interests. (English)
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