HIV and hepatitis C virus infection and co-infection among trans women in San Francisco, 2020 (Q28650)

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  • HIV and hepatitis C virus infection and co-infection among trans women in San Francisco, 2020.
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English
HIV and hepatitis C virus infection and co-infection among trans women in San Francisco, 2020
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  • HIV and hepatitis C virus infection and co-infection among trans women in San Francisco, 2020.

Statements

HIV and hepatitis C virus infection and co-infection among trans women in San Francisco, 2020. (English)
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Transgender women (hereafter "trans women") face social marginalization, stigma, and discrimination and experience a high burden of HIV. (English)
BACKGROUND (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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More recently, trans women have been identified as having a high risk for hepatitis C (HCV) infection. (English)
BACKGROUND (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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The interaction between these two diseases and the risks for HIV/HCV co-infection among trans women are understudied. (English)
BACKGROUND (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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To characterize epidemiological, behavioral, and socio-structural interactions between HIV and HCV infections among trans women. (English)
OBJECTIVE (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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This cross-sectional study examined data from a community-based survey of trans women in San Francisco recruited through respondent-driven sampling (RDS) in 2019/2020. (English)
METHODS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Face-to-face interviews collected data on demographics, medical history, drug injection practices, sexual behavior, and socio-structural factors (e.g., poverty, housing insecurity, incarceration, social support). (English)
METHODS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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HIV and HCV antibodies were detected using oral fluid rapid tests and prior diagnosis and treatment were collected by self-report. (English)
METHODS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Blood specimens were collected to confirm antibodies using ELISA. (English)
METHODS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Multinomial logistic regression analysis characterized factors associated with HIV infection alone, HCV infection alone, and HIV/HCV co-infection compared to neither infection. (English)
METHODS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Among 201 trans women recruited, HIV prevalence was 42.3%; HCV infection by history or current seroprevalence was 28.9%; evidence for both HIV and HCV infection was present for 18.9%. (English)
RESULTS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Two-thirds of trans women (67.2%) had been incarcerated; 30.8% had ever injected drugs. (English)
RESULTS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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History of injection drug use and receiving emotional support from family were factors found in common for HIV infection, HCV infection, and HIV/HCV co-infection compared to no infection. (English)
RESULTS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Having a sexual partner who injects drugs was associated with HIV infection alone. (English)
RESULTS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Not lacking care due to cost and older age were associated with co-infection. (English)
RESULTS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Older age was also associated with HCV infection. (English)
RESULTS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Of trans women with HIV infection, 91.8% had accessed HIV care, whereas only 62% with HCV had accessed some form of care. (English)
RESULTS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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Our study found high levels of HIV, HCV, and HIV/HCV co-infection among trans women in San Francisco. (English)
CONCLUSIONS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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We found common associations between HIV and HCV through injection practices and emotional support, but having a sexual partner who injects drugs was not associated with HCV infection alone or co-infection. (English)
CONCLUSIONS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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We note a substantial gap in the treatment of HCV for trans women, including those in HIV care, that needs to be urgently addressed. (English)
CONCLUSIONS (English)
Copyright: © 2024 Chiu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (English)
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2024
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2024
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9
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e0307990
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e0307990
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The authors have declared that no competing interests exist. (English)
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