Effects of HIV Self-Testing on Testing Promotion and Risk Behavior Reduction Among Transgender Women in China: Randomized Controlled Trial (Q27932)

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  • Effects of HIV Self-Testing on Testing Promotion and Risk Behavior Reduction Among Transgender Women in China: Randomized Controlled Trial.
  • Effects of HIV Self-Testing on Testing Promotion and Risk Behavior Reduction Among Transgender Women in China
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English
Effects of HIV Self-Testing on Testing Promotion and Risk Behavior Reduction Among Transgender Women in China: Randomized Controlled Trial
No description defined
  • Effects of HIV Self-Testing on Testing Promotion and Risk Behavior Reduction Among Transgender Women in China: Randomized Controlled Trial.
  • Effects of HIV Self-Testing on Testing Promotion and Risk Behavior Reduction Among Transgender Women in China

Statements

Effects of HIV Self-Testing on Testing Promotion and Risk Behavior Reduction Among Transgender Women in China: Randomized Controlled Trial. (English)
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To date, no randomized controlled trials have specifically addressed behavior changes after HIV self-testing (HIVST) among transgender women. (English)
BACKGROUND (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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This study aims to evaluate the effects of HIVST on changes in HIV testing behavior, frequency of condomless sex, and partner numbers among transgender women in China. (English)
OBJECTIVE (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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Participants were recruited from 2 Chinese cities using both online and offline methods. (English)
METHODS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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Transgender women were randomly assigned to receive an HIVST intervention. (English)
METHODS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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Data from the previous 3 months were collected at baseline, 3 months, and 6 months. (English)
METHODS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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The primary outcome was the mean change in the number of HIV tests among transgender women during the 6-month follow-up. (English)
METHODS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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An intention-to-treat analysis was conducted. (English)
METHODS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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The statistical analysis used analysis of covariance and linear mixed-effects models. (English)
METHODS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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From February to June 2021, and 255 transgender women were recruited, of which only 36.5% (93/255) had a steady job, and 27.1% (69/255) earned less than US $414.9 of income per month. (English)
RESULTS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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They were randomly assigned to the intervention (n=127) and control (n=128) groups. (English)
RESULTS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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At 6 months, the mean number of HIV tests was 2.14 (95% CI 1.80-2.48) in the intervention group and 1.19 (95% CI 0.99-1.40) in the control group (P<.001), with increases of 0.84 (95% CI 0.54-1.14) and 0.11 (95% CI -0.19-0.41) over 6 months, respectively. (English)
RESULTS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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The net increase was 0.73 (95% CI 0.31-1.15; P<.001), with a similar adjusted result. (English)
RESULTS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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No significant differences in the frequency of condomless sex or partner numbers were observed between the 2 groups. (English)
RESULTS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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HIVST is an effective strategy for enhancing regular HIV testing behavior among transgender women in China. (English)
CONCLUSIONS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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This strategy should be combined with measures to address the financial vulnerability of the transgender women community to reduce subsequent risk behaviors, including condomless sex. (English)
CONCLUSIONS (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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Chinese Clinical Trial Registry ChiCTR2000039766; https://www.chictr.org.cn/showproj.html?proj=61402. (English)
TRIAL REGISTRATION (English)
©Yan-Yan Zhu, Ze-Hao Ye, Zhen-Xing Chu, Yingjie Liu, Jie Wei, Le Jia, Yong-Jun Jiang, Hong Shang, Qing-Hai Hu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.10.2024. (English)
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29 October 2024
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29 October 2024
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