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  • The implications of hormone treatment for cancer risk, screening and treatment in transgender individuals.
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  • The implications of hormone treatment for cancer risk, screening and treatment in transgender individuals.

Statements

The implications of hormone treatment for cancer risk, screening and treatment in transgender individuals. (English)
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There is evidence that gender-affirming hormone treatment (GAHT) for transgender individuals modulates their risk for specific malignancies including breast and prostate cancer, and meningiomas. (English)
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. (English)
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However, there is insufficient data to make precise risk estimates accounting for age and inherited cancer risk. (English)
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. (English)
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As such, screening recommendations remain broad. (English)
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. (English)
1 reference
Even less evidence exists for best practice in the management of active or historical cancers in the transgender population. (English)
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. (English)
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Guidance is therefore mainly extrapolated from cisgender populations but with considerations of the significant benefits of GAHT in the face of any hormonal risk. (English)
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. (English)
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Clinical experience, the multidisciplinary team and shared decision making with the patient are vital in providing person-centred care, while further research is acquired. (English)
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. (English)
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September 2024
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September 2024
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38
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5
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101909
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101909
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S1521-690X(24)00063-0
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Declaration of Competing Interest AMB has received honoraria for non-promotional education on cancer care in transgender patients from Pfizer, Lilly and Astellas, and a fellowship grant to employ staff for the UK Cancer and Transition Service from Gilead. (English)
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SA declares no conflicts of interest. (English)
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