(Q32518)
Statements
The growing demographic presence of the transgender (TGD) population has sparked an increase in clinical investigations focusing on the impacts of gender-affirming hormone therapy (GAHT) in adults with gender dysphoria. (English)
INTRODUCTION (English)
© 2024. The Author(s). (English)
2024
Despite this surge in studies, there remains a significant gap in the literature regarding the health status of older TGD individuals. (English)
INTRODUCTION (English)
© 2024. The Author(s). (English)
2024
This review aims to assess prevalent pathological conditions within the TGD population, specifically concentrating on aging-related diseases investigated to date. (English)
INTRODUCTION (English)
© 2024. The Author(s). (English)
2024
A systematic search across Embase Ovid, Scopus, PubMed, Cochrane Library, and Web of Science databases was conducted to identify articles reporting on the aging process in TGD individuals. (English)
METHODS (English)
© 2024. The Author(s). (English)
2024
Methodological quality was evaluated using Newcastle-Ottawa Scale (NOS) scores. (English)
METHODS (English)
© 2024. The Author(s). (English)
2024
Initial database searches yielded 12,688 studies, which were refined to 18 through elimination of duplicates and title/abstract review. (English)
RESULTS (English)
© 2024. The Author(s). (English)
2024
Following a comprehensive appraisal, nine studies were included in the systematic review. (English)
RESULTS (English)
© 2024. The Author(s). (English)
2024
These articles, published between 2017 and 2023, involved a total of 5403 participants. (English)
RESULTS (English)
© 2024. The Author(s). (English)
2024
The evidence indicates a noteworthy percentage of the TGD population being at risk for cardiovascular diseases, experiencing depression or disability, and demonstrating hesitancy toward major recommended screening programs. (English)
RESULTS (English)
© 2024. The Author(s). (English)
2024
Limited studies on older TGD individuals highlight not only an organic risk of chronic diseases but also a cognitive/psychiatric risk that should not be underestimated. (English)
CONCLUSIONS (English)
© 2024. The Author(s). (English)
2024
Further research is imperative to deepen our understanding of the pathophysiological mechanisms involved in the health challenges faced by older TGD individuals. (English)
CONCLUSIONS (English)
© 2024. The Author(s). (English)
2024
M V (English)
Papa (English)
MV
All authors state that they have no competing interests. (English)