(Q31185)
Statements
How do adult transgender and gender diverse (TGD) people, who are infertile due to prior gender-affirming treatment, view their current infertility and their reproductive decisions made in the past? (English)
STUDY QUESTION (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
In a time where sterilization was mandatory, transgender adolescents prioritized gender-affirming treatment over their future fertility and would make the same choice today despite emotional challenges related to infertility experienced by some. (English)
SUMMARY ANSWER (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
Under transgender law in the Netherlands, sterilization was required for legal gender recognition until 2014, resulting in permanent infertility. (English)
WHAT IS KNOWN ALREADY (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
The long-term consequences of this iatrogenic infertility in transgender adolescents who have now reached adulthood remain underexplored. (English)
WHAT IS KNOWN ALREADY (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
Qualitative study design based on 21 in-depth one-on-one semi-structured interviews. (English)
STUDY DESIGN, SIZE, DURATION (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
TGD people in a stage of life where family planning may be a current topic were eligible for participation. (English)
PARTICIPANTS/MATERIALS, SETTING, METHODS (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
They all received gender-affirming treatment in adolescence prior to the legislation change in 2014. (English)
PARTICIPANTS/MATERIALS, SETTING, METHODS (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
A purposeful sampling technique was used from participants of another ongoing study. (English)
PARTICIPANTS/MATERIALS, SETTING, METHODS (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
Eleven people assigned female at birth and ten people assigned male at birth were included. (English)
PARTICIPANTS/MATERIALS, SETTING, METHODS (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
Interview transcripts were thematically analysed using a modified version of Braun and Clarke's six steps theory. (English)
PARTICIPANTS/MATERIALS, SETTING, METHODS (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
Six main themes were generated: (i) personal considerations regarding fertility and fertility preservation in the past; (ii) external considerations regarding fertility and fertility preservation in the past; (iii) current vision on past considerations and decisions; (iv) Current experiences and coping with infertility; (v) future family building; (vi) advice regarding fertility and [...] (English)
MAIN RESULTS AND THE ROLE OF CHANCE (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
Selection, recall, and choice supportive bias may play a role in interpreting our results. (English)
LIMITATIONS, REASONS FOR CAUTION (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
This study highlights the importance of tailored counselling and comprehensive information on fertility preservation for transgender individuals, especially adolescents, undergoing gender-affirming treatment. (English)
WIDER IMPLICATIONS OF THE FINDINGS (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
N/A. (English)
STUDY FUNDING/COMPETING INTEREST(S) (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
N/A. (English)
TRIAL REGISTRATION NUMBER (English)
© The Author(s) 2024. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. (English)
2024
J D (English)
Asseler (English)
JD
I (English)
de Nie (English)
I
F B (English)
van Rooij (English)
FB
T D (English)
Steensma (English)
TD
D (English)
Mosterd (English)
D
M O (English)
Verhoeven (English)
MO
M (English)
Goddijn (English)
M
J A F (English)
Huirne (English)
JAF
N M (English)
van Mello (English)
NM
6 September 2024
4 September 2024
The authors declare no conflict of interest. (English)
declare that their department (reproductive medicine) have received research and educational grants from Guerbet, Merck, and Ferring (all location VUmc), outside the scope of the submitted work. (English)
received grants from ZonMw, Samsung, and PlantTec MedicalGmbH outside the scope of the submitted work. (English)
received grants from ZonMw, NWO, kinderpostzegels, and municipalities outside the scope of the submitted work. (English)