(Q30535)
Statements
Sexual minority women (SMW) and transgender and/or nonbinary (TNB) people report more adverse health outcomes (e.g., depression, anxiety, posttraumatic stress, substance use) relative to heterosexual, cisgender people, often due to the additional stress burden from experiencing stigma. (English)
OBJECTIVE (English)
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2024
Physiological and emotional stress reactivity are mechanisms through which high cumulative stress contributes to adverse health outcomes. (English)
OBJECTIVE (English)
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2024
The randomized controlled trial (RCT) described in this study protocol examines whether a single-session compassion microintervention may attenuate physiological and emotional stress reactivity to the minority stress Trier Social Stress Test (MS-TSST) among SMW/TNB people. (English)
OBJECTIVE (English)
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2024
This study will also examine whether the compassion microintervention reduces depression, anxiety, posttraumatic stress symptoms, and substance use from baseline to one-month follow-up, and assess microintervention acceptability. (English)
OBJECTIVE (English)
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2024
This protocol describes a two-arm parallel RCT. (English)
METHODS (English)
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2024
Participants are recruited online and at in-person events (e.g., Pride events). (English)
METHODS (English)
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2024
Participants complete baseline measures online (e.g., demographics, anxiety symptoms) and then complete an in-person lab visit that includes the compassion microintervention (or no training control). (English)
METHODS (English)
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2024
Immediately after the intervention period, participants complete the MS-TSST. (English)
METHODS (English)
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2024
Measures of physiological (i.e., blood pressure, cortisol) and emotional (i.e., negative affect, state anxiety) reactivity are collected throughout the lab visit. (English)
METHODS (English)
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2024
Participants also complete a one-month follow-up survey. (English)
METHODS (English)
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2024
Participants randomized to the microintervention are invited to complete a semi-structured virtual interview about their experiences to assess acceptability. (English)
METHODS (English)
Copyright © 2024 Elsevier Inc. All rights reserved. (English)
2024
Findings from this study could provide initial evidence that compassion microinterventions show promise in addressing stigma-related stress reactivity among SMW/TNB people. (English)
CONCLUSION (English)
Copyright © 2024 Elsevier Inc. All rights reserved. (English)
2024
govregistration:NCT05949060. (English)
CLINICALTRIALS (English)
Copyright © 2024 Elsevier Inc. All rights reserved. (English)
2024
Emily C (English)
Helminen (English)
EC
Kriti (English)
Behari (English)
K
Jillian R (English)
Scheer (English)
JR
12 September 2024
12 September 2024
Declaration of competing interest The authors declare no conflicts of interest. (English)